Laboratory of Endocrinology
Selected Publications ...Selected Conference Presentations ...Clinical Trials
Main Research Field
Diabetic Complications: Clinical and Translational Research
Research Subjects
- Angiogenesis and inflammation in diabetes
- Genetics of diabetic vascular complications
- Glycemic variability and glucose trend prediction
- Assessment of new antidiabetic drugs
- Osteoporosis in diabetes
Topics of research
Study of lymphatic system and connective tissue in endocrine pathology
Reconstruction and bioinformatics analysis of gene networks, identification of biomarkers of diabetic complications and osteoporosis
Technology development for analysis and prediction of glycemia in diabetes
Generation of new methods of diagnosis, treatment and prevention of diabetic complications based on molecular profiling and digital technologies
Assessment of new drugs for the treatment of diabetes and endocrine diseases
Head of Laboratory
Professor Vadim V. Klimontov, MD, PhD
Dr. V. Klimontov graduated from the Medical Faculty of Novosibirsk Medical Institute in 1996. He took postgraduate courses in Endocrinology and Diabetology at the Research Center of Endocrinology (Moscow), Oxford Centre for Diabetes, Endocrinology and Metabolism, and Erasmus University Medical Center in Rotterdam. He also had a set of clinical trainings at University Hospital Salzburg. In 2008 he completed his PhD-thesis on the mechanisms of development and the makers of initial stages of chronic kidney disease in patients with type 1 diabetes.
Prof. V. Klimontov carried out complex studies of the initial structural and functional changes in diabetic kidneys, and proposed some innovative tests to diagnostics of the initial stages of diabetic kidney disease. He also has been involved in genetic studies of diabetic vascular complications in Siberia. His current research interests include diabetes-related chronic low-grade inflammation and angiogenesis impairment, the assessment of glucose variability and prediction of glucose trends, as well as innovative antidiabetic modalities. As Deputy Director for Science, Prof. V. Klimontov coordinates the research activity in the Research Institute of Clinical and Experimental Lymphology - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.
Prof. V. Klimontov is a member of European Association for the Study of Diabetes (EASD) and American Diabetes Association (ADA). Since 2000, he presents his works regularly at EASD, ADA and IDF meetings. His projects had been supported by the grants from EASD, RF Presidential Council, and Russian Science Foundation. Dr. V. Klimontov is an author of more than 100 articles in peer-review journals and a member of the editorial boards of "World Journal of Diabetes" and "Diabetes Mellitus". He carried out the peer-reviews for “Acta Diabetologica”, “World Journal of Diabetes”, “Genes”, “Bulletin of the Russian Academy of Medical Sciences”, “Diabetes Mellitus”, “Biochemistry”, “Obesity and Metabolism”, and others journals. In 2016 Dr. V. Klimontov was awarded the honorary title of Professor of the Russian Academy of Science (RAS). He works as an expert for RAS, Russian Federal Agency of Scientific Organizations, and Russian Science Foundation.
Research Group
Dr. Elena Koroleva, MD, PhD
Dr. Elena Koroleva graduated from the Medical Faculty of the Novosibirsk State Medical Institute in 1995. She had her residency in Internal Medicine and took some postgraduate training courses in Endocrinology and Diabetology. In 2005 she received her PhD in Endocrinology with a focus on diabetic cardiovascular autonomic neuropathy. She joined Laboratory as a senior researcher in 2015 being a Head of Endocrinology Department at the institute clinic.
Dr. E. Koroleva has 15 years of experience in randomized clinical trials. Her current research interests include the pathogenesis, genetics and clinical course of atherosclerosis in diabetic subjects. She is an author of 20 articles in peer-reviewed journals and co-author of one monograph.
Dr. Dinara Bulumbaeva, MD
Dr. D. Bulumbaeva graduated from Medical Faculty of Novosibirsk State Medical University in 2013 and she had her residency in Endocrinology at Novosibirsk State Medical University. She joined Laboratory as a junior researcher in 2015.
She performed the study of clinical and ultrasound characteristics of insulin-induced lipohypertropthy in patients with diabetes. Currently she is involved in the study of the markers and mechanisms of adipose tissue dysfunction in subjects with type 2 diabetes. The results of the study were presented at some national and international conferences, including the meetings of European Association for the Study of Diabetes and American Diabetes Association. She is an author of 8 articles in peer-reviewed journals.
Dr. Olga Fazullina, MD
Dr. O. Fazullina graduated from Medical Faculty of Novosibirsk State Medical University in 2005. She had her residency in Internal Medicine and Endocrinology at Novosibirsk State Medical University. She also took some training courses in Clinical Densitometry and Osteoporosis. She joined Laboratory as a junior researcher in 2012.
Dr. O. Fazullina is a member of the Russian Osteoporosis Association and Russian Association of Endocrinologists. Her research activity is concentrated on genetics and pathogenic mechanisms of osteoporosis in patients with type 2 diabetes. She presented the results of her study at some national and international conferences, including the meetings of Russian Osteoporosis Association and Russian congresses on Diabetes. She is an author of 8 articles in peer-reviewed journals.
Dr. Anton Korbut, MD
Dr A. Korbut graduated from Medical Faculty of Novosibirsk State University in 2013 and trained as a resident in Internal Medicine and Endocrinology at Scientific Institute of Clinical and Experimental Lymphology and Novosibirsk State Medical University. He joined Laboratory as a junior researcher in 2016.
Currently he is involved in the basic study of DPP-4 and SGLT2 inhibitors in diabetic kidney disease. He trained in the working with diabetic laboratory animals and oversees the light and electron microscopy and immunohistochemistry of kidney samples. He is an author of 4 articles in peer-reviewed journals.
Сontacts
Arbuzov Street 6, 630117, Novosibirsk, Russia
Tel. +7-383-335-96-33
E-mail: klimontov@mail.ru
